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Tumor Glomus

Abstract

Glomus tumors are a very rare mesenchymal neoplasm, it happen less than 2% of all soft tissue tumors. It can be benign, borderline and malignant. The most common location were subungual, however it also can grow at the body organ and extremities. A 60-year-old male patient with firmly defined 1,5 cm diameters tumor mass at the proximal 1/3 proximal cruris region. He was complaining long history of pain and it spreading from the lesion area to the sole of the foot in the last 1 year occasionally. The pain improves at rest. An excisional biopsy was performed with macroscopic features of rounded tissue gray-white color and tender. On microscopic examination, there are neoplastic cell proliferation arranged in a solid pattern, with spherical cell morphology, amphophilic to eosinophilic cytoplasm with spherical nucleus in the middle without atypical nuclear sign. Besides that, there is focal area of stromal hyalinization. No visible mitosis. Based clinical and histopathology feature, the patient is diagnosed as a glomus tumor. The prognosis is quite good because the location and size of the tumor allowing for complete surgical excision and the possibility of recurrence are very rare.

 

Tumor glomus merupakan neoplasma mesenkimal yang sangat jarang, hanya kurang dari 2% dari seluruh tumor jaringan lunak. Tumor ini dapat bersifat jinak, borderline dan ganas. Lokasi tumor tersering adalah di subungual namun dapat juga terjadi di organ dalam maupun ekstremitas. Pasien laki-laki, 60 tahun dengan massa tumor ukuran diameter 1,5 cm berbatas tegas pada regio cruris dekstra 1/3 proksimal, mengeluh nyeri timbul saat sentuhan dan terkadang menjalar dari daerah lesi ke telapak kaki sejak 1 tahun terakhir. Nyeri tersebut membaik saat istirahat. Telah dilakukan biopsi eksisi pada tumor tersebut dengan gambaran makroskopisjaringan berbentuk bulat, warna putih abu-abu dan kenyal ukuran 0,8 × 0,7 × 0,3cm. Pada pemeriksaan mikroskopis ditemukan proliferasi sel neoplastik yang membentuk pola solid, dengan morfologi sel bentuk bulat, sitoplasma amphofilik sampai eosinofilik dan inti bulat di tengah tanpa tanda atipia inti. Di sekitar sel tumor tampak fokus stroma yang mengalami hialinisasi. Tidak tampak mitosis. Pasien di diagnosis sebagai tumor glomus. Prognosis pasien ini baik karena lokasi dan ukuran tumor yang memungkinkan untuk dilakukan eksisi pembedahan dan kemungkinan terjadinya rekurensi sangat jarang.

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How to Cite

Paskarani, P. E., & Winarti, N. W. (2020). Tumor Glomus. Medicina, 51(2), 128–131. https://doi.org/10.15562/medicina.v51i2.977

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