GRAVES DISEASE IN A 16 YEAR-OLD FEMALE: A CASE REPORT
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- DOI: https://doi.org/10.15562/medicina.v50i1.349  |
- Published: 2019-02-13
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Google Scholar | PubMed | Medicina Journal
GRAVES DISEASE IN A 16 YEAR-OLD FEMALE: A CASE REPORT
Ni Wayan Yuliandari, I Made Arimbawa
Department of Child Health, Faculty of Medicine-Udayana University
Sanglah Public Hospital-Bali
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ABSTRACT
Graves’ Disease is an autoimmune disease which is originated from production of Thyroid-Stimulating Immunoglobulins leading to overproduction of thyroid hormone. Most Graves’ disease case reported to date are associated with adults, which makes extrapolation of the result to children and adolescents particularly challenging. A 16-year-old female presented with a slowly-enlarging painless mass in her front neck over a three-year period, sensation that food is getting stuck in the upper throat, lack of concentration and attentiveness, and easily feelings fatigue. Her aunty has a history of Struma surgical treatment. Thyroid Ultrasound, thyroid function tests, Thyroid Peroxidase Antibody, and Thyroglobulin Antibody revealed Graves’ disease. She takes 5 mg of Thiamazole once daily and shows improvement after four weeks.
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Keywords: Graves’ disease, autoimmune, family history
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ABSTRAK
Penyakit Graves’ adalah penyakit autoimun yang disebabkan oleh produksi Thyroid-Stimulating Immunoglobulins berlebih sehingga menghasilkan kelebihan hormon tiroid. Penyakit ini umumnya terjadi pada orang dewasa dan jarang ditemukan pada remaja maupun anak-anak. Seorang remaja perempuan datang dengan pembesaran pada leher bagian depan, tidak terasa sakit, kadang merasa terganjal pada kerongkongan, mudah lelah, dan kehilangan konsentrasi sejak 3 tahun lalu. Terdapat riwayat operasi struma pada bibi pasien. Ultrasonografi tiroid, fungsi tiroid, dan pemeriksaan antibodi tiroid menyokong adanya Penyakit Graves’. Tablet Thiamazole sebanyak 5 mg diberikan sekali sehari dan terdapat perbaikan kondisi maupun laboratorium dalam waktu empat minggu.
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Kata kunci: Graves’ disease, autoimmune, family history
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