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Korelasi antara kadar serum albumin dan status fungsional pada pasien geriatri di RSUP Sanglah Denpasar, Bali

Abstract

Status fungsional adalah kemampuan untuk melakukan aktivitas sehari-hari dan merupakan aspek penting dalam penilaian kualitas hidup. Status fungsional secara umum ditentukan oleh status nutrisi, kemampuan otot serta adanya penyakit komorbiditas. Kadar albumin yang rendah sering terjadi pada kondisi status nutrisi yang buruk dan penyakit inflamasi terutama pada geriatri yang akan mempengaruhi kemampuan otot pada geriatri. Tujuan penelitian ini adalah menilai korelasi antara kadar serum albumin dan status fungsional pada pasien geriatri. Penelitian ini berupa studi potong lintang analitik. Kriteria inklusi adalah semua pasien usia ≥ 60 tahun dengan penyakit medis tertentu yang rawat inap di RSUP Sanglah pada bulan November 2014 sampai dengan Februari 2015. Kriteria eksklusi adalah pasien dengan keganasan, riwayat operasi, trauma dan penggunaan obat psikoaktif serta data rekam medik tidak lengkap saat penelitian berlangsung. Kadar albumin serum diperiksa di laboratorium dengan metode bromcresol green dan status fungsional diperiksa dengan kuesioner Activity Daily Living (ADL) Barthel. Sampel penelitian ini berjumlah 72, dengan kadar albumin rata-rata adalah 2.99 ± 0.72 g/dl. Prevalensi hipoalbuminemia adalah 75% dan 46,2% pasien mengalami ketergantungan total. Kadar albumin berkorelasi positif dengan status fungsional pada pasien geriatri (r=-0.254; p=0.031) dengan interval kepercayaan 95%.



Functional status is the ability to perform daily activities and a key aspect of the quality of life and also  a strong predictor of survival. In the other hand low serum albumin level is the result of the combined effects of inflammation and malnutrition in elderly. This study aims to determine whether there is a correlation between serum albumin levels with functional status in elderly patient in hospital. This study was designed with cross-sectional method using the analytical observational was conducted with purposive sampling. Subject is elderly patients (≥60 years) admitted to Sanglah hospital Denpasar, Bali, Indonesia, between November 2014-February 2015 (n=72). Serum albumin level was examined in the laboratory used bromcresol green method and functional status was measured with activities of daily living (ADL) Barthel questionnaire. Nonparametric spearman’s test was used to analyze the correlation between serum albumin with functional status and data were presented with 95% confidence interval. 72 samples were obtained in the study with a mean albumin level of 2.99 ± 0.72 g/dl. The prevalence of hypoalbuminemia (<3.5 g/dl) was 75% and 46.2% with total dependency. Positive correlation Spearman’s test was statistically significant between albumin serum and functional status (r=0.254; p=0.031).

 

 

References

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How to Cite

Desy Lestari, D. N., & Kuswardhani, R. A. T. (2019). Korelasi antara kadar serum albumin dan status fungsional pada pasien geriatri di RSUP Sanglah Denpasar, Bali. Medicina, 50(2). https://doi.org/10.15562/medicina.v50i2.337

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Desak Nyoman Desy Lestari
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Medicina Journal


Raden Ayu Tuty Kuswardhani
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Pubmed
Medicina Journal