Skip to main content Skip to main navigation menu Skip to site footer

Karakteristik pasien traumatik optik neuropati (TON) yang mendapat terapi kortikosteroid dosis tinggi dibandingkan dengan observasi di RSUP Sanglah Denpasar tahun 2013-2015

Abstract

Traumatic optic neuropathy (TON) is a potential blinding complication of head or orbital trauma. The injury impact may generate a shock wave which lead to optic nerve avulsion or indirect TON. Theraphy for TON remains controversial. The objective of this research is focus on characteristic and difference improvement of visual acuity between TON patient treated by high-dose corticosteroid and observation in Sanglah general hospital Denpasar. This research is a descriptive study using retrospective data of 41 patients with TON attending Sanglah General Hospital Denpasar, from January 2013 until December 2015. The data were analyzed descriptively, shown as frequency and percentage. Improvement of visual acuity were analyzed by chi-square test. Fourthy-one patients were included, 13 patiens received high dose corticosteroid and 28 patients received observation. In corticosteroid group, 84.6% were males, number of patients who were less than 20 years old is the highest (46.2%), mayority came from Denpasar (53.8%), most of the eyes had poor vision on presentation (6/60-NLP) with majority of patients (83%) presented with maxillofacial trauma, head injury with cranial base fracture. In clinical observation group, 78.6% were males, number of patients who were less than 20 years old is the highest (50%), mayority came from Denpasar (23.1%), most of the eyes had poor vision on presentation (6/60-NLP), majority of patients (23.1%) had head injury and maxillofacial trauma. This study concluded that there is no statistically significant difference in improvement of visual acuity ≥ 2 line between patients treated by high-dose corticosteroid and observation.

 

 

References

  1. Steinsapir KD dan Goldberg RA. Perspective traumatic optic neuropathy: An evolving understanding. Elsevier. 2011;151(6):928-33.
  2. Yu-Wai-Man P dan Griffiths PG. Steroids for traumatic optic neuropathy. Cochrane database of systemic reviews. 2013;6:1-21.
  3. Levin LA, Beck RW, Joseph MP, Seiff S, Kraker R. The international optic nerve trauma study: the treatment of traumatic optic neuropathy. Ophthalmology. 1998;106:1268–77.
  4. Sundeep, Niveditha H, Nikhil N, Vitutha BV. Visual outcome of traumatic optic neuropathy in patients treated with intravenous methylprednisolone. International Journal of Scientific Study. 2014;2(3):67-70.
  5. Lee KF, Nor NI, Yaakub A, Hitam WH. Traumatic optic neuropathy: a review of 24 patients. International Journal of Ophthalmology. 2010;3(2):175-8.
  6. Maliawan S, Mahadewa TG, Mas AA. Lateral orbitotomy for traumatic optic neuropathy and traumatic opthalmoplegia: is it beneficial ?. Neurology Asia. 2009;14:35-9.
  7. American Academy of Ophthalmology Staff. Neuro-Ophthalmology, Basic and clinical science course, Section 5. San Francisco:2014-2015.
  8. Rajiniganth MG, Gupta AK, Gupta A, Bapuraj JR. Traumatic optic neuropathy: visual outcome following combined therapy protocol. Arch Otolaryngol Head Neck Surg. 2003;129:1203-6.
  9. Wang AG. How to manage traumatic optic neuropathy? Taiwan Journal of Ophthalmology. 2015;5:1-2.
  10. Wu N, Yin ZQ, Wang Y. Traumatic optic neuropathy therapy: an update of clinical and experimental studies. The Journal of International Medical Research. 2008;36:883–9.
  11. Levin LA. Traumatic optic neuropathy. Dalam: Roy FH dan Fraunfelder F, penyunting. Roy and Fraunfelder’s Current Theraphy. Edisi ke-6. Philadelphia: Saunders; 2007. h. 75-9.

How to Cite

Mahayani, N. M. W. (2017). Karakteristik pasien traumatik optik neuropati (TON) yang mendapat terapi kortikosteroid dosis tinggi dibandingkan dengan observasi di RSUP Sanglah Denpasar tahun 2013-2015. Medicina, 48(3). https://doi.org/10.15562/medicina.v48i3.159

HTML
41

Total
121

Share

Search Panel

Ni Made Widya Mahayani
Google Scholar
Pubmed
Medicina Journal