Prevalens dan karakteristik penderita retinoblastoma di RSUP Sanglah Denpasar pada tahun 2008-2015
- PDF  |
- DOI: https://doi.org/10.15562/medicina.v49i2.109  |
- Published: 2018-07-16
Retinoblastoma is the most common intraocular malignancy of childhood, with incidence 1 in 20.000 birth and 3-4% of all malignant tumors in children. There has been no data about the prevalence and characteristics of children with retinoblastoma in Sanglah Hospital, Denpasar. Aim of this study is to know prevalence and characteristics of children with retinoblastoma in Sanglah Hospital, Denpasar. This is retrospective study, conducted in Sanglah Hospital, Denpasar, performedÂ by data obtained from January 2008 to December 2015. The prevalence of retinoblastoma among children with solid tumor from January 2008 to December 2015 was 72% (59 of 82 cases). There were 75% cases unilateral and 25% bilateral. The female to male ratio was 1:1.2, with mean age when admitted was 31.4 (18.8 SD) months. There was 64% from Bali, 24% West Nusa Tenggara and 12% East Nusa Tenggara. Fourty six percent with well nourished and 37% mild malnourhised. The most common presenting sign when admitted was proptosis (64%) and leukocoria (27%). First leucocyte count 10.7 103/ÂµL (3.5 SD), haemoglobin 11.7 g/dL (1.3 SD), platelet count 448 103/ÂµL (188.5 SD) and 21 cases (36%) with thrombocytosis. The mortality was 68% and three cases (5%) lost to follow up. The Conclusions is prevalence of retinoblastoma in Sanglah Hospital was 72% with mortality 68%. Mostly occurs in males, mean age when admitted was 31.4 (18.8 SD) months, mostly unilateral, with the most common presenting sign was proptosis. Leucocytes and haemoglobin mostly normal and 36% with thrombocytosis.